女性生殖器恶性肿瘤致心包积液——附9例报告及文献复习

目的 探讨女性生殖器恶性肿瘤致心包积液的临床特点和诊断治疗。方法 回顾性分析了我院４０年间诊治的生殖器恶性肿瘤致心包积液９例的临床特点、诊断及治疗。结果 ９例中６例卵巢恶性肿瘤（４例卵巢上皮性癌,２例卵巢弥漫性颗粒细胞瘤）、２例宫颈癌、１例子宫内膜癌,平均年龄４１．６岁。诊断原发肿瘤到心包积液的间隔时间为２￣４９个月。临床症状多表现为胸闷和呼吸困难。９例经胸部Ｘ线诊断,其中６例同时经Ｂ超诊断,３例

Female malignant tumors of genital organs with pericardial effusion: report of 9 cases and review of literatures

OBJECTIVE: To study the clinical characteristics and the management of malignant tumors of genital organs with pericardial effusion. METHODS: Nine cases of gynecologic malignant tumors with pericardial effusion were analyzed retrospectively. RESULTS: Nine cases of gynecologic malignant tumors were separated into 4 cases of epithelial ovarian carcinoma, 2 cases of diffuse ovarian granulosa cell tumor, 2 cases of cervix carcinoma and 1 case of endometrial carcinoma. The mean age was 41.6 years, the intervals from primary tumors to pericardial effusions were 2-49 months. The clinical symptoms were mainly severe shortness of breath. Nine cases were diagnosed by chest X-rays, 6 of them were confirmed by B ultrasonography simultaneously. Three cases were given pericardiocentesis and their cytologic examinations were positive. Two cases of ovarian malignant tumors have been surviving for 49 and 12 months respectively after pericardiocentesis with local chemotherapy and effective systemic chemotherapy, 1 case was survived for 5 months by hormone therapy, but 6 untreated cases were died of cardiac tamponade within one month. CONCLUSIONS: Malignant tumors of genital organs with pericardial effusion could be definitely diagnosed by X-ray, B ultrasonography and cytology. The surviving period may be prolonged by pericardio centesis combined with systemic effective chemotherapy.