晚期卵巢上皮性癌腹膜后淋巴结清的合理选择

目的 探讨腹膜后淋巴结清除术在晚期卵巢上皮性癌治疗中的合理应用。方法 对４２例晚期卵巢上皮性癌行腹膜后淋巴结清除术,根据术后钱留灶大小成分两组。Ａ组：２６例,残留癌灶直径２〈ｃｍ;Ｂ组：１６例,残留癌灶直径≥２ｃｍ。术后两组进行的联合化疗基本相同。临床分期和病理分级基本相同。结果 Ａ组５年生存率５３．８％（１４／２６）,Ｂ组５年生存率１２．５％（２／１６）,两组比较,差异有显著意义（Ｐ〈０．００１

A rational selection of retroperitoneal lymphadenectomy for advanced epithelial ovarian cancer

OBJECTIVE: To evaluate the rational application of retroperitoneal lymphadenectomy to advanced epithelial ovarian cancer. METHODS: 42 patients of advanced epithelial ovarian cancer were treated by retroperitoneal lymphadenectomy. Two groups were divided according to the residual disease post-operation. A: 26 patients with the residual disease < 2 cm; B: 16 patients > or = 2 cm. The regime of combined chemotherapy was the same in the two groups after operation. Clinical stage and pathologic grade showed no difference. RESULTS: The 5-year survival rate was 53.8% (14/26) in A and 12.5% (2/16) in B. There was a significant difference between the two groups (P < 0.001). CONCLUSIONS: The survival rate could be greatly improved for advanced epithelial ovarian cancer through retroperitoneal lymphadenectomy when the residual disease was smaller than 2 cm. This procedure would not be performed if the residual disease was larger than or equal to 2 cm.