| 白细胞介素6在早产胎膜早破孕妇血清及胎膜组织中的表达 |
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| 引用本文： | Zhao Y,Li S,Tong X. 白细胞介素6在早产胎膜早破孕妇血清及胎膜组织中的表达[J]. 中华妇产科杂志, 1999, 0(3): 138-139 |
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| 作者姓名： | Zhao Y Li S Tong X |
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| 作者单位： | 北京医科大学第三临床医院妇产科,北京民航总医院 |
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| 摘 要： | 探讨白细胞介素６在早产胎膜早破孕妇血清中的水平及其在胎膜组织中的表达与早产胎膜早破的方法。方法采用酶联免疫吸附法和免疫组化方法,对３０例早产胎膜早破孕妇和２０例正常孕妇血清中ＩＬ－６水平及肥膜组织ＩＬ－６蛋白表达进行检测。结论ＩＬ－６与感染引起的早产有关。
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| 关 键 词： | 白细胞介素6 胎膜早破 早产 |
Serum concentration of interleukin-6 in maternal serum and its expression in amniochorionic membranes of preterm premature rupture of membrane |
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| Zhao Y,Li S,Tong X. Serum concentration of interleukin-6 in maternal serum and its expression in amniochorionic membranes of preterm premature rupture of membrane[J]. Chinese Journal of Obstetrics and Gynecology, 1999, 0(3): 138-139 |
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| Authors: | Zhao Y Li S Tong X |
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| Affiliation: | Third Hospital, Beijing Medical University, Beijing 100083. |
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| Abstract: | OBJECTIVE: To investigate the relationship between interleukin-6 (IL-6) and preterm premature rupture of membranes (PPROM). METHODS: Serum IL-6 in 20 cases of normal pregnancy (control group) and 30 cases with PPROM in which 14 had moderate and severe chorioamnionitis (group 1), 16 had no chorioamnionitis (group 2) were measured by enzyme-linked immunosorbent assay (ELISA), and IL-6 protein in fetal membranes were determined by immunohistochemistry technique. RESULTS: The level of serum IL-6 in group 1 (155.17 ng/L) was significantly higher than that in group 2 (79.11 ng/L) and control group (70.15 ng/L) (P < 0.01). Expression of the IL-6 had more positive signs in chorion with chorioamnionitis, especially in infiltrating inflammatory cells. CONCLUSION: IL-6 associated with the onset of preterm labor caused by infection. |
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