经阴道输卵管插管行配子输卵管移植的临床初步研究

目的 了解经阴道配子输卵管移植治疗非输卵管性不孕症（子宫内膜异位症、男性少弱精症、不明原因不孕等）的效果。方法 对２１例（２３个周期）不孕症患者分别采用（１）绝经期促性腺激素（ｈＭＧ）／ｈＣＧ（７个周期）;（２）卵泡刺激素（ＦＳＨ）／ｈＣＧ（２个周期）;（３）短方案促性腺激素释放激素激动剂（ＧｎＲＨ－ａ）／ｈＭＧ／ｈＣＧ（２个周期）;（４）长方案ＧｎＲＨ－ａ／ＦＳＨ／ｈＭＧ／ｈＣＧ（１２个周期）进

Tubal catheterization for transvaginal gamete intrafallopian transfer: an alternative technique for non-tubal infertility

OBJECTIVE: To evaluate the outcome of transvaginal gamete intrafallopian transfer (TV-GIFT) for infertile patients with non-tubal factors. METHODS: Controlled ovarian hyperstimulation was used for all patients. Transvaginal ultrasound-guided oocyte retrieval followed by tubal catheterization for transvaginal gamete intrafallopian transfer of 3.3 +/- 2.1 oocytes (range 1-8) and 200,000 sperms in 50 microliters culture medium. RESULTS: The TV-GIFT was used in total of 23 treatment cycles. Of 23 cycles performed for TV-GIFT, the procedure was completed easily in 18 and difficult in 5, resulting in 5 clinical pregnancies(21.7% per cycle), 2 of which resulted in abortion, 2 ongoing pregnancy one was ectopic pregnancy. No pregnancy occurred in four cycles with only one oocyte transferred. CONCLUSIONS: Simple and cost-effective TV-GIFT may achieve a higher pregnancy rate. Compared with laparoscopically directed GIFT, tubal catheterization for TV-GIFT is safe and less invasive. It is an alternative for non-tubal infertility before entering the IVF-ET program.