| 孕妇血清中乙型肝炎病毒DNA含量与胎儿宫内感染的关系 |
| |
| 引用本文： | Liu Z,Xu D,Yan Y. 孕妇血清中乙型肝炎病毒DNA含量与胎儿宫内感染的关系[J]. 中华妇产科杂志, 1999, 0(3): 133-134 |
| |
| 作者姓名： | Liu Z Xu D Yan Y |
| |
| 作者单位： | 第四军医大学流行病学教研室,陕西省妇幼保健院 |
| |
| 摘 要： | 探讨孕妇血清中乙型肝炎病毒ＤＮＡ含量与胎儿宫内感染发生率的关系。方法用斑点杂交法检测１８５例乙型肝炎病毒表面抗原阳性孕妇血清中ＨＢＶＤＮＡ及新生儿ＨＢｓＡｇ。结论孕妇血清ＨＢＶＤＮＡ含量升高是胎儿发生乙型肝炎病毒感染重要因素之一。
|
| 关 键 词： | 疾病传播 乙型肝炎病毒 DNA 宫内感染 |
The relationship of serum hepatitis B virus DNA load in HBsAg positive pregnant women to the intrauterine infection of newborns |
| |
| Liu Z,Xu D,Yan Y. The relationship of serum hepatitis B virus DNA load in HBsAg positive pregnant women to the intrauterine infection of newborns[J]. Chinese Journal of Obstetrics and Gynecology, 1999, 0(3): 133-134 |
| |
| Authors: | Liu Z Xu D Yan Y |
| |
| Affiliation: | Fourth Military Medical University, Xi' an 710033. |
| |
| Abstract: | OBJECTIVE: To study the relationship of serum hepatitis B virus (HBV) DNA load in HBsAg positive pregnant women to intrauterine infection of their newborns. METHODS: Serum HBV DNA were determined by dot-blot hybridization in 185 HBsAg positive pregnant women. Serum HBsAg were tested by ELISA in their newborns within 24 hours after birth. RESULTS: The prevalence of intrauterine HBV infection of the newborns was associated with the HBV DNA level of the mothers. With the increase of serum HBV DNA load, the risk of fetal intrauterine infection was increasing. CONCLUSION: Fetal exposure to high level of maternal HBV DNA is one of the important determinant of intrauterine infection. |
| |
| Keywords: | |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ |
