| 高效液相色谱法和分光光度法测定双氯芬酸钠乳膏含量的研究 |
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| 引用本文： | 张晓乐,段京莉,叶国庆,严宝霞.高效液相色谱法和分光光度法测定双氯芬酸钠乳膏含量的研究[J].中国药学杂志,1996,31(3):159-161. |
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| 作者姓名： | 张晓乐 段京莉 叶国庆 严宝霞 |
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| 作者单位： | 北京医科大学第三医院药剂科 |
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| 摘 要： | 目的：研究和寻找精密而简便地测定双氯芬酸钠乳膏含量的方法。方法：采用高效液相色谱法和紫外分光光度法。结果：两种方法的平均回收率(X%)及变异系数(RSD%)分别为99.46±0.91和99.70±0.92。结论：结果表明，两种方法均可用于双氯芬酸钠乳膏的含量测定，但HPLC更适于成品含量测定和杂质检查。而UV法可用于生产过程中的半成品检验。
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| 关 键 词： | HPLC UV 双氯芬酸钠 |
HPLC and UV for concentration determination of diclofenac sodium cream |
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| Zhang Xiaole.HPLC and UV for concentration determination of diclofenac sodium cream[J].Chinese Pharmaceutical Journal,1996,31(3):159-161. |
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| Authors: | Zhang Xiaole |
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| Institution: | (Zhang XL),Duan Jingli(Dugn JL),Ye Guoqing(Ye GQ),et a |
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| Abstract: | To find a precise,simple and convenient method for concentration determination of diclofenac sodium cream. METHODS :HPLC and UV were used to determine its concentration. RESULTS:Analytical recoveries of HPLC and UV were 99.46%and 99.70%respectively. The RSD was 0.9l%of HPLC and 0.92%for UV.CONCLUSION:The results show that the former can be used to determine finished product and impurity check up and the latter to determine sime-finished product. |
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| Keywords: | HPLC UV diclofenac sodium |
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