Genetic polymorphism of 15 STR loci in central western Colombia |
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| Institution: | 1. Medical Genetic Laboratory of Universidad Tecnológica de Pereira, Colombia;2. Forensic Science Department of Universidade de Santiago de Compostela, Spain;1. Department of Genetics and Evolution, Institute of Zoology, Jagiellonian University, Kraków, Poland;2. Department of Dermatology, Collegium Medicum of the Jagiellonian University, Kraków, Poland;3. Department of Forensic Molecular Biology, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands;4. Department of Legal Medicine, Osaka City University Medical School, Osaka, Japan;5. Division of Legal Medicine, Faculty of Medicine, Tottori University, 86 Nichicho, Yonago, Japan;6. Section of Forensic Genetics, Institute of Forensic Research, Kraków, Poland;7. Yale Molecular Anthropology Laboratory, Department of Anthropology, Yale University, 10 Sachem Street, New Haven, CT 06511, USA;1. Biochemistry Department, University of Medicine and Pharmacy Victor Babes, Timisoara, Romania;2. Department of Public Health, University of Medicine and Pharmacy Victor Babes, Timisoara, Romania;3. Deparment of Legal Medicine, University of Medicine and Pharmacy Victor Babes, Timisoara, Romania;4. Institute of Legal Medicine, Timisoara, Romania;1. GENES SAS Laboratory, Medellín, Colombia;2. School of Medicine, University of Campinas, São Paulo, Brazil;3. School of Health Sciences, Pontificia Bolivariana University, Medellín, Colombia;4. Institute of Biology, University of Antioquia, Medellín, Colombia;5. Directorate of Criminal Investigation and Interpol, Policía Nacional, Bogotá, Colombia;6. IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Portugal;1. Laboratorio de Genética Molecular Cruz Vital, Cruz Roja Ecuatoriana, Quito, Ecuador;2. Laboratorio GENES Ltda, Medellín, Colombia;1. Instituto de Investigaciones Biomédicas, Universidad de las Américas, Quito – Ecuador;2. Grupo Investigación Identificación Genética IdentiGEN, Universidad de Antioquia, Medellín – Colombia;3. Laboratorio de Genética Molecular, Cruz Vital - Cruz Roja Ecuatoriana, Quito – Ecuador;4. Grupo de Investigación de Biotecnología. Instituto de Biología, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia, Medellín – Colombia;5. Laboratorio de Genética, Instituto Nacional de Medicina Legal y Ciencias Forenses, Bogotá – Colombia |
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| Abstract: | Fifteen autosomal short tandem repeat (STR) loci were analyzed using the AmpFISTR Identifiler PCR Amplification Kit in 1944 samples of healthy unrelated individuals, born in the regions of Caldas, Quindio and Risaralda, Colombia. Allele frequencies and statistical parameters of forensic interest are presented for all markers (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, THO1, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA). All loci of the pooled data were in agreement with Hardy–Weinberg equilibrium, after Bonferroni correction. Comparisons with neighboring Latin American populations and Andalucia (Spain) revealed significant differences in allele distributions. Genetic data presented in this study can be used for routine forensic applications in the region. |
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