维持性血液透析患者并发肺动脉高压影响因素分析

目的探讨维持血液透析患者并发肺动脉高压（PAH）的发生率及发生PAH的相关影响因素。方法对61例维持性血液透析患者进行超声心动图检查,以是否合并有肺动脉高压,将研究对象分为肺动脉高压组和无肺动脉高压组,检测两组性别、年龄、血压、透析龄、每周透析时间、血管通路（动静脉内瘘、非动静脉内瘘）、血红蛋白、血尿素氮、血肌酐、血钙、肺动脉收缩压、左房收缩末内径（LA）、左室舒张末内径（LVd）、左室收缩末内径（LVs）、室间隔舒张期厚度（IVs）、左室射血分数（LVEF）,并进行统计学分析。结果 61例患者中,超声心动图发现肺动脉高压24例,发生率39.3%,其中轻度13例（54.2%）,中度9例（31.5%）,重度PAH 2例（8.3%）。PAH组与无PAH组左房收缩末横径、左室收缩末内径（LVs）、室间隔舒张期厚度（IVs）、左室射血分数（LVEF）比较,差异有统计学意义（P〈0.05）。室间隔舒张期厚度（IVs）与维持性血透患者并发PAH有相关性（P〈0.05）。结论维持性血液透析患者并发PAH不少见,本研究中MHD并发PAH患者左心功能下降,室间隔舒张期厚度（IVs）与肺动脉高压发生有相关性。

Analysis of correlative factors of pulmonary hypertension in maintenance hemodialysis patients

Objective To investigate the incidence and the correlative factors in maintenance hemodialysis patients with pulmonary hypertension(PAH).Methods The incidence of PAH was estimated with Doppler echocardiography in 61 hemodialysis patients.The clinical data were collected and analyzed.Results 24 patients(39.3%) were found having PAH including 13 mild PAH,9 moderate PAH and 2 severe PAH.There were significant difference of the left atrium diameter(LA),left ventricular end-systolic diameter(LVs),interseptal ven...