中晚期原发性肝癌的预后因素分析

目的：探讨有关临床因素对中晚期肝癌预后的影响。方法：收集350例原发性肝癌患的诊治信息，应用Kaplan-Meier法和COX模型对一些临床因素进行生存及预后因素分析。结果：失6访率28.6%，全组1，3，5年生存率分别为38%，12.1%，6.9%。多因素COX模型分析显示影响中晚期肝癌的临床预后因素为：临床分期、治疗方法及肝内播散等。结论：临床分期、治疗方法等临床因素可作为判断中晚期肝癌预后的指标。具有一定的临床参考价值。

Analysis of Prognostic Factors of Advanved Hepatocellular Carvinoma

Objective:To explore influence of some clinical factors on prognosis of advanved hepatovellular carcinoma.Methods:350 cases with hepatocellular carcinoma were selected to sutdy.using Kaplem-Meier's methoed and COX model,analysis of susrvival and prognostic factors were performed to some clinical factors.Ressults:The result showed that rate of loss to follow-up was 28.6% and the over-all survival rates were 38% at one year 12.1% at 3 year and 6.9%.at 5 years separately.The result of multivariae COX model analysis showed that the significant prognostic factors were clinical stage,methods of treatment and spread in liver,Conclusion:Clinical factors of clinical stage and methods of treatment et al were the indexes for indentifing the prognosis of hepatocellular caroinoma.;