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Orthostatic heart rate responses after prolonged space flights
Authors:Jens Tank  Roman M. Baevsky  Irina I. Funtova  André Diedrich  Irina N. Slepchenkova  Jens Jordan
Affiliation:(1) Institute of Clinical Pharmacology, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany;(2) Institute of Biomedical Problems, Moscow, Russia;(3) Division of Clinical Pharmacology, Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN, USA
Abstract:Orthostatic tachycardia (POTS) can occur after space flights. We determined orthostatic heart rate responses in 18 cosmonauts before and 3–5 days after long-term space missions. Cosmonauts undergoing a cardiovascular training program in space experienced only moderate POTS after their return to earth. Cardiovascular countermeasures may have attenuated POTS. Another possible interpretation is that cardiovascular deconditioning is not sufficient to elicit full blown POTS in the absence of additional genetic or environmental factors.
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