PET-CT显像肺癌晚期治疗后随访中的应用价值

目的：探讨18F 脱氧葡萄糖(FDG)正电子发射计算机摄影（PET）与CT（PET CT）显像在肺癌治疗后随访中的临床应用价值。方法：使 用PET CT显像对42例肺癌患者(28例经手术治疗、8例化学治疗、6例放射治疗)进行疗效随访观察，随访时间为治疗后6个月～3年。并将PET CT与CT扫描结果进行比较。结果：42例中有16例在原发肿瘤病灶区域发现复发，其中有8例PET CT显示肿瘤原发灶区域复发而CT未能检出。复 发灶的标准摄取值（SUV）平均值为6.43，其周围纤维灶SUV平均值为1.6。18例检出不同程度的转移，其中，全身多发性转移有12例，局限性单 发性转移有6例。在18例转移患者中，有4个纵隔转移淋巴结，CT显示其大小在正常范围，有3处远处骨转移，CT未能检出。结论：FDG PET CT 显像在肺癌治疗后病灶的复发或转移的监测中有较大的临床应用价值。

Role of 18F-FDG PET-CT in follow-up of lung neoplasms after treatment

Objective: To evaluate the effect of ~18F-FDG PET-CT in follow-up of lung cancer after treatment.Methods: ~18F-FDG PET-CT was used to evaluate the effect of 42 patients with lung cancer from 6 months to 3 years after treatment and compared with results from CT imaging.Of them,28 were treated by surgery,8 by chemotherapy,and 6 by radiotherapy.Results:Relapse in the same place of the primary focus was found in 16 patients,of whom 8 were found by ~18F-FDG PET-CT but none by CT imaging.Average standard uptake value(SUV) of recrudescence was 6.43,and the average SUV of fiber around the recrudescence was 1.6.Metastasis in different degree was found in 18 patients,of whom 12 were in multimode.6 were single metastasis in localization;Lymphous metastasis in 4 patients was found in natural size by CT imaging,but osteal metastasis in 3 patients was not found by CT imaging.Conclusion: ~18F-FDG PET-CT has salutary effect in detecting the recrudescence and metastasis of lung cancer after treatment.