动脉粥样硬化性疾病患者血粘度和凝血纤溶动态图的变化

目的探讨血粘度和凝血纤溶动态图在动脉粥样硬化性疾病中的变化及意义。方法采用ＦＡＳＣＯ－９４全自动粘度快测仪和凝血纤溶动态图仪对３８例动脉粥样硬化性疾病患者和３０例正常对照进行血粘度和凝血纤溶动态图的测定。结果血粘度指标中除血沉和血沉方程Ｋ值外，全血粘度、血浆粘度、红细胞压积、全血还原粘度、红细胞聚集指数、红细胞变形指数均显著性高于对照组（Ｐ<０．０３５～０．００１）；凝血纤溶动态图中的凝血指标凝固启动时间、１分钟凝固程度、最大凝固程度、到达最大凝固时间和纤溶指标平衡时间、１分钟纤溶程度、完全溶解时间、平均溶解程度较对照组有显著性差别（Ｐ< ０．０３６～０．００１）。结论动脉粥样硬化性疾病患者存在血液高凝状态和高粘血症，并且两者相互影响。

Changes of Both Blood Viscosity and Coagulation and Fibrinolysis Dynamicagram(CFDG)in Patients with Atherosclerotic Diseases

Objective To inquire into changes and meanings of both blood viscosity and CFDG in patients with atherosclerotic diseases. Methods We apply FASCO-94 viscosity and CFDG instrument for 38 patients with atherosclerotic diseases and 30 healthy subjects. Results Except erythrocyte sedimentation rate (ESR) and ESR equation K value, whole blood viscosity, plasmatic viscosity, hemocytotripsis.whole blood restoring viscosity,red cell glutination index,red cell deforming index in the indexes of blood viscosity were significantly higher than those of the normal group (P<0.035-0.001 ). There was significant difference of coagulation and fibrinolysis indexes of CFDG between two groups(P <0.036-0.001 ). Conclusion patients with atherosclerotic diseases exist hypercoagulable state and hyperviscosity syndrome and both have reciprocal causation.