高血压并发心脑靶器官损害的动态血压特征

目的探讨高血压有心脑合并症时的昼夜血压变化的规律。方法６８例高血压患者中１６例有左室肥厚，１６例有左室肥厚伴脑血管意外，１２例有脑血管意外；２４例未发现有心脑并发症作为对照。全部患者作动态血压测定。结果有并发症的三组患者以收缩压和舒张压共同升高，夜间下降率＜１０％，血压昼夜波动成为非杓型为特点。心室肥厚组日间血压和对照组无明显差异，而脑血管意外组具有清晨血压升高的特点。结论血压的昼夜波动变化与高血压患者合并症的发生有密切关系。

The Characteristics of Ambulatory Blood Pressure Monitoring in Hypertensive Patients with Damage of Target Organs

Aim\ To investigate the characteristics of ABPM in patients of hypertension complicated with damages in end target organs.\ Methods\ Sixty eight hypertensive patients including 16 cases of left ventricular hypertrophy,12 cases of cerebrovascular attack,16 cases of ventricular hypertrophy complicated with cerebrovascular attack, and 24 cases of uncomplicated hypertension.\ All were studied with ambulatory blood pressure monitoring. \ Results\ The nondipper type of SBP and DBP at night time was the characterstic findings among the three complicated groups.\ The decrease rate of blood pressure was less than 10% in simple ventricular hypertrophy group, no SBP increase in day time. However, the increases of SBP in the morning is exclusive findings in the hypertensive patients with brain damaged. \ Conclusion\ Target organs damage in hypertensive patients usually accompanies with the changes of circadian changes of blood pressure.