| 高血压患者脂质过氧化物及白细胞介素Ⅱ的相关性 |
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| 引用本文： | 费瑜 刘万车. 高血压患者脂质过氧化物及白细胞介素Ⅱ的相关性[J]. 高血压杂志, 1997, 5(3): 222-223 |
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| 作者姓名： | 费瑜 刘万车 |
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| 作者单位： | 白求恩医科大学第二临床学院心内科 |
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| 摘 要： | 目的探讨脂质过氧化物（ＭＤＡ）及白细胞介素Ⅱ（ＩＬ－２）。方法用硫代巴比妥酸微量法及双抗夹心法测定４６例高血压患者及２０例健康的ＭＤＡ和ＩＬ－２。结果高血压患者ＭＤＡ明显高于健康对照组（Ｐ＜０．０５）而高血压患者ＩＬ－２明显低于对照组（ｒ＝－０．７３２，Ｐ＜０．０５）。结论高血压患者存在ＭＤＡ和ＩＬ－２异常，ＩＬ－２与ＭＤＡ有内在联系，氧自由基（ＯＦＲ）损伤淋巴细胞可能是导致ＩＬ－２异常的原因之一。
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| 关 键 词： | 高血压；白细胞介素Ⅱ；丙二醛 |
Correlation of Lipid Peroxidation Product and Interleukin 2 in Patients with Essential Hypertension |
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| Fei Yu,Liu Wanche,Chen Lijuan. Correlation of Lipid Peroxidation Product and Interleukin 2 in Patients with Essential Hypertension[J]. Chinese Journal of Hypertension, 1997, 5(3): 222-223 |
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| Authors: | Fei Yu Liu Wanche Chen Lijuan |
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| Abstract: | Aim To explore correlation and founction of interleukin 2(IL 2) and malondialdehyde(MDA) in thirty three patients with essential hypertension(EH) and compared with normal control subjects. Methods IL 2 and MDA were measured by enzymelinked immunoassay and thiobarbiturates method. Results MDA was sigmificantly higher and IL 2 was significantly lower(P<0.05) in EH than normal subjects.Linear correlation between IL 2 and MDA was r=-0.732,P<0.05. Conclusion MDA had negative correlation with IL 2,lower of IL 2 may be ascribed to the more production of oxidative free radical. |
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| Keywords: | essential hypertension interleukin 2 malondialdehyde |
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