| 53味清热类中药对绿脓杆菌抑菌作用的聚类分析 |
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| 引用本文： | 何先元,李坤,喻录容,刘俊康,廖巳祥,刘艳霞. 53味清热类中药对绿脓杆菌抑菌作用的聚类分析[J]. 中国实验方剂学杂志, 2014, 20(20): 222-225 |
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| 作者姓名： | 何先元 李坤 喻录容 刘俊康 廖巳祥 刘艳霞 |
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| 作者单位： | 重庆医科大学中医药学院, 重庆 401331;重庆医科大学中医药学院, 重庆 401331;重庆医科大学中医药学院, 重庆 401331;第三军医大学微生态药学, 重庆 400038;重庆医科大学中医药学院, 重庆 401331;第三军医大学微生态药学, 重庆 400038 |
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| 基金项目： | 重庆市卫生局科技项目（2012-2-144） |
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| 摘 要： | 目的:通过对53味清热类中药对绿脓杆菌的抑菌作用的聚类分析,了解它们抑菌效果的差异,指导临床用药。方法:通过药敏纸片法测定抑菌环直径和液体培养测定吸光度(A)确定中药的抑菌效果。结果:聚类分析表明清热中药抑制绿脓杆菌效果的类群与传统分类存在不一致现象。结论:临床上对于防治绿脓杆菌的感染,可选用赤芍、胡黄连、黄连、蒲公英、丝瓜络、黄芩、密蒙花等清热类中药。
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| 关 键 词： | 清热类中药 绿脓杆菌 抑菌效果 聚类分析 |
| 收稿时间： | 2013-10-31 |
Cluster Analysis of 53 Chinese Antipyretic Herbs on Bacteriostatic Effects Against Pseudomonas Aeruginosa |
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| HE Xian-yuan,LI Kun,YU Lu-rong,LIU Jun-kang,LIAO Si-xiang and LIU Yan-xia. Cluster Analysis of 53 Chinese Antipyretic Herbs on Bacteriostatic Effects Against Pseudomonas Aeruginosa[J]. China Journal of Experimental Traditional Medical Formulae, 2014, 20(20): 222-225 |
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| Authors: | HE Xian-yuan LI Kun YU Lu-rong LIU Jun-kang LIAO Si-xiang LIU Yan-xia |
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| Affiliation: | College of Traditional Chinese Medical, Chongqing University of Medical Sciences, Chongqing 401331, China;College of Traditional Chinese Medical, Chongqing University of Medical Sciences, Chongqing 401331, China;College of Traditional Chinese Medical, Chongqing University of Medical Sciences, Chongqing 401331, China;Microbial Pharmacy of Third Military Medical University, Chongqing 400038, China;College of Traditional Chinese Medical, Chongqing University of Medical Sciences, Chongqing 401331, China;Microbial Pharmacy of Third Military Medical University, Chongqing 400038, China |
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| Abstract: | Objective: The bacteriostatic effects of 53 Chinese antipyretic herbs against pseudomonas aeruginosa and their antibacterial difference were classified and confirmed by cluster analysis in order to instruct clinical administration. Method: Antibacterial effect of traditional Chinese medicine was ascertained by determination of diameter of inhibition zone K-band in liquid culture. Result: The cluster analysis showed that the classification of bacteriostatic Pseudomonas aeruginosa effects were not consistent with traditional classification of Chinese antipyretic herbs group. Conclusion: For the clinical prevention of P. aeruginosa infection, the optional Chinese antipyretic herbs were suggested as paeoniae radix rubra, picrorhizae rhizoma, coptidis rhizoma, taraxaci herba, luffae fructus retinervus, scutellariae radix, buddlejae flos, etc. |
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| Keywords: | Chinese antipyretic herbs Pseudomonas aeruginosa antibacterial effect cluster analysis |
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