Merkel cell carcinoma with bone metastasis: a case report |
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Authors: | Akira Kamijo Tomihisa Koshino Kazuo Hirakawa Tomoyuki Saito |
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Institution: | (1) Department of Orthopaedic Surgery, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan, JP |
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Abstract: | A case of Merkel cell carcinoma with bone metastasis is described. The patient, who had a history of Merkel cell carcinoma
of the skin in the right cheek, had spontaneous pain in the right thigh. At the initial visit, the right hip range of motion
was slightly limited, but there was no gait disturbance or abnormality in the radiographs of the right hip. However, the pain
gradually increased and caused gait disturbance. The patient underwent surgical treatment. A bipolar type of femoral prosthesis
was implanted into the femur, and sampling of cancellous bone was performed at the time of osteotomy. Pathological examination
showed the findings of Merkel cell carcinoma. Merkel cell carcinoma is a rare malignant tumor of the skin, which usually occurs
on the head, neck, or extremities and metastasizes to the lymph nodes. Although osseous involvement often occurs in the adjacent
facial bones through direct invasion, distant osseous metastasis appears to be extremely rare.
Received: November 12, 2001 / Accepted: April 18, 2002 |
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Keywords: | Merkel cell carcinoma Bone metastasis Pathological fracture Metastasis via lymph nodes |
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