Surface structure of virions budding from L1210(V) gln- mouse leukemia cells. |
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| Authors: | A Demsey T A Calvelli D Kawka C W Stackpole N H Sarkar |
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| Affiliation: | Memorial Sloan-Kettering Cancer Center, Walker Laboratory, Rye, New York, USA |
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| Abstract: | The surface structure of virions budding from L1210(V) gln? murine leukemia cells was studied by freeze-drying intact cells, and two types of virus particles were detected. One type possessed random 10-nm surface projections, similar to budding viruses on cells producing only murine leukemia virus (MuLV). The other type possessed regularly arranged 5-nm projections, similar to budding viruses on cells producing only murine mammary tumor virus (MuMTV). Results of double antibody labeling are in agreement with the indication that individual viral envelopes on L1210(V) gln? cell viruses are homogeneous in their surface structure. |
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| Keywords: | Author to whom reprint requests should be addressed. |
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