Pentacam分析仪测量近视眼患者角膜厚度及影响因素分析

目的使用Pentacam眼前节分析系统测量近视患者角膜中央最薄点厚度,并探讨与A型超声角膜测厚仪测量结果的差异及可能影响因素。方法对预行准分子激光角膜手术的近视患者150例(300眼),分别采用Pentacam系统及A型超声角膜测厚仪测量角膜中央最薄点厚度,对测量结果进行统计学分析。结果 Pentacam、A型超声角膜测厚仪测得的中央角膜最薄点厚度平均值分别为(543.7±26.3)μm、(539.2±27.4)μm,二者高度相关(r=0.97,P=0.0001)。Pentacam测得角膜厚度值偏厚,二者差值平均(4.4±7.0)μm,差异有统计学意义(t=10.94,P=0.0001),该差值与A型超声测量角膜厚度值、年龄有关(P=0.0001),而与屈光度、性别、角膜直径、角膜曲率等无关。结论 Pentacam测量近视患者角膜厚度值略高于A型超声角膜测厚仪,尽管二者有很好的协同性,但相互间还不能完全替代。

Corneal thickness measured by Pentacam in myopic eyes and its related factors analysis

Objective To compare the difference of the thinnest central corneal thickness in myopic eyes using Pentacam and A-scan ultrasound pachymetry,and assess the related effective factors.Methods The thinnest central corneal thickness in 300 eyes of 150 myopic patients before laser refractive surgeries was measured by Pentacam and A-scan ultrasonic pachymetry.The differences in the measurements obtained by two methods were statistically analyzed.Results The thinnest central corneal thickness measured by Pentacam and A-scan ultrasonic pachymetry were(543.7±26.3)μm and(539.2±27.4)μm,respectively,the correlation between them was high(r=0.97,P=0.000 1).The thickness measured by Pentacam was thicker than that by A-scan ultrasonic pachymetry,the difference was(4.4±7.0)μm,there was significant difference(P=0.000 1).The difference was correlated with the corneal thickness measured by A-scan ultrasonic pachymetry and the age(P=0.000 1),while there was no correlation with refractive power,gender,corneal diameter and corneal curvature.Conclusion The corneal thickness measured by Pentacam is thicker than that by A-scan ultrasound pachymetry in myopic eyes.Although they have well cooperativity,they cannot be simply used interchangeably.