光动力三阶段疗法治疗肛周尖锐湿疣的临床观察

目的:采用光动力三阶段疗法治疗肛周尖锐湿疣,观察疗效及复发率.方法:将我科门诊肛周尖锐湿疣患者随机分成治疗组(45例)、对照组(35例),分别采用冷冻、光动力疗法及局部免疫调节剂分三个阶段治疗和单纯采用冷冻治疗.比较两组患者的疗效和复发率.结果:治疗组治愈率97.78%,对照组治愈率65.72%;两组患者治疗结束后第4,8和12周时的复发率差异和治愈率均有统计学意义(P均<0.05).结论:肛周尖锐湿疣进行三阶段治疗,能明显降低复发率,疗效优于单一疗法.

Photodynamic three step therapy in the treatment of perianal condyloma acumininatum

Objectives: To observe the effect of photodynamic 3 step therapy in the treatment of perianal condyloma acuminatum.Method: Perianal condyloma acuminata patients in our department were randomly divided into the treatment group(n=45) and the control group(n=35).The treatment group was applied with 3 step therapy,namely,cryotherapy,photodynamic and topical immunomodulator therapy.The control group was only treated with cryotherapy.The two groups of patients were compared in the curative efficacy and the recurrence rate.Results: The curative efficacy is 97.78%in the treatment group,and 65.72% in the control group.The two groups showed significant differences in the efficacy and recurrence rates after 4,8 and 12 weeks of treatment(P<0.05).Conclusion: Photodynamic 3 step therapy is effective in the treatment of perianal condyloma acuminate and can reduce the recurrence rate.