| 伊曲康唑治疗ICU侵袭性真菌感染的临床分析 |
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| 引用本文： | 张久之,万献尧,黄日红,吴向东.伊曲康唑治疗ICU侵袭性真菌感染的临床分析[J].大连医科大学学报,2008,30(5):441-443. |
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| 作者姓名： | 张久之 万献尧 黄日红 吴向东 |
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| 作者单位： | 大连医科大学,附属第一医院中心ICU,辽宁,大连,116011;大连医科大学,附属第一医院中心ICU,辽宁,大连,116011;大连医科大学,附属第一医院中心ICU,辽宁,大连,116011;大连医科大学,附属第一医院中心ICU,辽宁,大连,116011 |
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| 摘 要： | 目的]评估伊曲康唑治疗ICU中危重患者侵袭性真菌感染（IFI）的疗效及安全性。方法]回顾性分析37例ICU中诊断IFI的危重患者资料。观察疗效、用药时间与预后、不良反应。结果]总有效率78.38%（29/37）,白色念珠菌感染患者有效率83.33%（20/24）,光滑假丝念珠菌感染患者有效率63.64%（7/11）,热带念珠菌感染患者有效率50%（2/4）。确诊病例有效率75%（3/4）,临床诊断病例有效率80%（24/30）,拟诊病例有效率66.67%（2/3）。不良反应发生率37.84%（14/37）。不良反应症状较轻、可逆,对症处置后好转,无需停药。结论]早期经验性应用伊曲康唑治疗ICU危重患者IFI疗效明确、安全,但应加强监测。
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| 关 键 词： | 伊曲康唑 侵袭性真茵感染 ICU |
Analisys of efficacy and safety of itraconazloe in treating patients with invasive fugal infection in ICU |
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| ZHANG Jiu-zhi,WAN Xian-yao,HUANG Ri-hong and WU Xiang-dong.Analisys of efficacy and safety of itraconazloe in treating patients with invasive fugal infection in ICU[J].Journal of Dalian Medical University,2008,30(5):441-443. |
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| Authors: | ZHANG Jiu-zhi WAN Xian-yao HUANG Ri-hong and WU Xiang-dong |
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| Institution: | Department of Center ICU;the First Affiliated Hospital of Dalian Medical University;Dalian 116011;China |
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| Abstract: | Objective] To evaluate the efficacy and safety of itraconazloe in treating the invasive fugal infection(IFI) in ICU.Methods] To reviewed retrospectively the clinical data of 37 patients with the invasive fugal infection in ICU of our hospital.The patients were given itraconazole injection by intravenous infusion,d 1~2.200 mg/d,bid;hereafter 200 mg/d;or/and,simultaneously with observation of clinical efficacy,safty,drug administration time and prognosis,adverse reactions.Results] The total clinical effica... |
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| Keywords: | itraconazloe IFI ICU |
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