| 卵母细胞的细胞质体外成熟的观察指标 |
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| 引用本文： | 胥玉梅,张梅心,李娟. 卵母细胞的细胞质体外成熟的观察指标[J]. 生殖医学杂志, 2009, 18(1): 71-74. DOI: 10.3969/j.issn.1004-3845.2009.01.021 |
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| 作者姓名： | 胥玉梅 张梅心 李娟 |
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| 作者单位： | 山东省计划生育科学技术研究所,济南,250002 |
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| 摘 要： | 卵母细胞体外成熟（IVM）培养过程中还存在很多问题，胞核和胞质成熟的不同步直接影响了卵母细胞的发育能力，从而影响了IVM的成功率。在探讨人未成熟卵母细胞IVM的各种影响因素时，对细胞质成熟一直缺乏有效的观察、评价指标，从而影响了研究进程。本文就IVM中卵母细胞成熟胞质的一般形态、超微结构以及可能影响胞质成熟的特异性表达基因做简要综述。
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| 关 键 词： | 卵母细胞 体外成熟 细胞质 线粒体 皮质颗粒 基因 |
Markers of cytoplasmic maturation of in-vitro matured human oocytes |
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| XU Yu-mei,ZHANG Mei-xin,LI Juan. Markers of cytoplasmic maturation of in-vitro matured human oocytes[J]. Journal of Reproductive Medicine, 2009, 18(1): 71-74. DOI: 10.3969/j.issn.1004-3845.2009.01.021 |
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| Authors: | XU Yu-mei ZHANG Mei-xin LI Juan |
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| Affiliation: | (Reproductive Medical Center of Shandong Family Planning Institute, J inan 250002) |
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| Abstract: | Many factors influence the process of in-vitro maturation （IVM） of oocytes. The successful development of the oocytes depends on the coordination of oocyte nuclear and cytoplasmic maturation. Until now no effective markers can ensure the assessment of cytoplasmic maturation of oocyte. The article reviewed the general morphology and ultrastructure of oocyte matured cytoplasm, and specially expressed genes which may influence cytoplasmic maturation in IVM. |
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| Keywords: | Oocyte In-vitro maturation Cytoplasml Mitochondria Cortical granule Gene |
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