Human T-cell leukemia virus type II infection among high risk groups and its influence on HIV-1 disease progression |
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Authors: | Dr Magnani Giacomo Elia Gian Franco Casoli Claudio Calzetti Carlo Degli Antoni Anna Donatini Anna Fiaccadori Franco |
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Affiliation: | (1) Cattedra di Malattie Infettive dell' Universià di Parma, via Gramsci 14, I-43100 Parma, Italy;(2) Istituto di Patologia Medica, Università degli Studi di Parma, Italy |
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Abstract: | The prevalence and the risk factors of the human T-cell leukemia virus type I/II (HTLV-I/II) infection were evaluated among 552 individuals at high risk for HIV-1. HTLV infections showed a low (1.6%) prevalence, were restricted to intravenous drug addicts and were due to HTLV-II alone. Moreover, in order to weigh the influence of HTLV-II on the natural history of HIV-1 infection, the clinical outcome of HIV-1 disease was compared between subjects with and without HTLV-II coinfection. Our findings showed that HTLV-II does not adversely affect the outcome of HIV-1 infection. Infact, a slower disease progression has been recorded in some HTLV-II coinfected subjects. |
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Keywords: | HTLV-II virus HTLV-II/HIV-1 coinfection Seroprevalence |
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