Demographic, family, and occupational characteristics associated with major depression: the Harvard study of moods and cycles |
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Authors: | Harlow B L Cohen L S Otto M W Liberman R F Spiegelman D Cramer D W |
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Institution: | The Obstetrics and Gynecology Epidemiology Center at Brigham and Women's Hospital and Harvard Medical School, Massachusetts 02115, USA. |
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Abstract: | OBJECTIVE: This study assesses the extent to which women with and without major depression differ by demographic, familial, and occupational characteristics. METHOD: From a community-based sample, the authors identified 332 women with and 644 women without current or past major depression based on Structured Clinical Interviews for DSM-IV. Demographic and background interviews were conducted in-person. RESULTS: Depressed women were more likely to have gained >or =35 lbs between age 18 and study enrollment (OR=1.6, 95% CI 1.1-2.5), experienced divorce (OR=2.0, 95% CI 1.4-2.8), or changed occupations (OR=1.5, 95% CI 1.1-2.1) compared with non-depressed women. Compared with women with no brothers, those with > or =1 brothers were less likely to have a history of depression (OR=0.8, 95% CI 0.6-1.1), whereas compared with women with no sisters, those with > or =1 sisters were more likely to have current or past depression (OR=1.4, 95% CI 1.0-1.9). These findings were not influenced by family sibship size. CONCLUSION: These results illustrate demographic differences between women with and without major depression and that sibship gender rather than size may also influence risk. |
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Keywords: | major depression risk factors sibship occupation epidemiologic studies |
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