Amrinone for refractory cardiogenic shock following chloroquine poisoning |
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| Authors: | Dr Ph Hantson J L Ronveau B De Coninck J L Horn P Mahieu A Hassoun |
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| Institution: | (1) Département des Soins Intensifs, Cliniques St. Luc, Avenue Hippocrate, 10, B-1200 Brussels, Belgium;(2) Laboratory of Toxicology, Cliniques Universitaires St-Luc, Brussels, Belgium |
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| Abstract: | Cardiac arrhythmias and circulatory collapse account for the high mortality reported after severe chloroquine poisoning. We have recently observed a 17-year-old man who ingested an 8 g chloroquine overdose. Cardiac arrest occurred within 1 h. Cardiogenic shock was refractory to epinephrine, dopamine and molar sodium lactate. Amrinone, a bipyridine analog, was then successfully used to improve haemodynamic conditions. |
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| Keywords: | Chloroquine poisoning Cardiogenic shock Epinephrine Amrinone |
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