醋酸钙片治疗腹膜透析患者高磷血症的疗效观察 |
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引用本文: | 孙岩,兰超,张菁菁,陈李萨,热娜,赵新,李素华,王梅红,刘珍,桑晓红,刘健. 醋酸钙片治疗腹膜透析患者高磷血症的疗效观察[J]. 中国中西医结合肾病杂志, 2013, 0(9): 784-786 |
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作者姓名: | 孙岩 兰超 张菁菁 陈李萨 热娜 赵新 李素华 王梅红 刘珍 桑晓红 刘健 |
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作者单位: | 新疆医科大学第一附属医院肾内科 |
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基金项目: | 新疆医科大学内科重点专科建设项目 |
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摘 要: | 目的:观察醋酸钙片治疗腹膜透析患者高磷血症的临床疗效。方法:41例CAPD腹膜透析伴有高磷血症患者,口服醋酸钙片治疗,观察8周。检测治疗前、治疗2周、4周和8周血磷、血钙、碱性磷酸酶和全段甲状旁腺激素等。结果:与治疗前比较,治疗2周、4周、8周血磷明显下降,差异有统计学意义(P值〈0.05);与治疗前比较,治疗2、4、8周校正血钙、白蛋白、血红蛋白、血肌酐、全段甲状旁腺激素和碱性磷酸酶差异均无统计学意义(P〉0.05)。醋酸钙片治疗高磷血症总有效率82.93%,轻度不良反应发生率4.88%,高钙血症2例,发生率4.88%。结论:醋酸钙片治疗腹膜透析患者高磷血症具有明显疗效且安全。
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关 键 词: | 醋酸钙片 腹膜透析 高磷血症 |
Efficacy and Safety of Calcium Acetate for the Treatment of Peritoneal Dialysis with Hyperphosphatemia |
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Affiliation: | SUN Yan;LAN Chao;ZHANG Jingjing;Department of Nephrology,the First Affiliated Hospital of Xinjiang Medical University; |
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Abstract: | Objective:To evaluate the efficacy and safety of calcium acetate for the treatment of peritoneal dialysis patients with hyperphosphatemia. Methods:41 cases Continuous ambulatory peritoneal dialysis patients with hyperphosphatemia, received calcium acetate treatment for 8 weeks. Serum phosphorus, calcium, alkaline phosphatase and intact parathyroid hormone (iPTH)were assessed at 2, 4 and 8 weeks after treatment. Results:Serum phosphorus was declined significantly after 2 ,4 and 8 weeks of treatment compared with the baseline (P 〈 0.05 ), while the levels of serum calcium, hemoglobin, albumin, serum creatinine and intact parathyroid hormone showed no significant difference(P 〉 0.05 ). The total effective rate was 82.93% after treatment, while the incidence of mild adverse reaction was 4.88%, and hypercalcemia in 2 patients was observed, the incidence was 4.88%. Conclusion :Calcium acetate for the treatment of peritoneal dialysis patients with hyperphosphatemia has obvious efficacy and safety. |
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Keywords: | Calcium acetate Peritoneal dialysis Hyperphosphatemia |
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