| 正交试验法优选功血饮颗粒的醇提工艺 |
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| 引用本文： | 陆元元,毛春芹,谈瑄忠,陆兔林,李莉. 正交试验法优选功血饮颗粒的醇提工艺[J]. 安徽医药, 2010, 14(3): 270-272. DOI: 10.3969/j.issn.1009-6469.2010.03.008 |
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| 作者姓名： | 陆元元 毛春芹 谈瑄忠 陆兔林 李莉 |
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| 作者单位： | 南京中医药大学,江苏,南京,210046;南京市中医院,江苏,南京,210001 |
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| 基金项目： | 南京中医药大学科技创新风险基金项目(No012073002013);;南京市科技局立项资助(No2005-0497) |
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| 摘 要： | 目的优选功血饮颗粒的最佳醇提工艺。方法采用正交试验法，以芍药苷和人参皂苷Rg1及浸出物为指标，对功血饮颗粒的醇提工艺进行优选。结果最佳醇提工艺为：加饮片总量为18倍量的70％乙醇分3次回流提取，每次2h。结论该工艺稳定，可行。
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| 关 键 词： | 功血饮颗粒 芍药苷 人参皂苷Rg1 醇提工艺 |
Optimizing the alcohol extracting process for gongxueyin granules by orthogonal test |
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| LU Yuan-yuan,MAO Chun-qin,TAN Xuan-zhong,LU Tu-lin,LI Li. Optimizing the alcohol extracting process for gongxueyin granules by orthogonal test[J]. Anhui Medical and Pharmaceutical Journal, 2010, 14(3): 270-272. DOI: 10.3969/j.issn.1009-6469.2010.03.008 |
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| Authors: | LU Yuan-yuan MAO Chun-qin TAN Xuan-zhong LU Tu-lin LI Li |
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| Affiliation: | 1.Pharmaceutical College of Nanjing University of Traditional Chinese Medicine;Nanjing;Jiangsu 210046;China;2.Nanjing Hospital of Traditional Chinese Medicine;Nanjing 210001;China |
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| Abstract: | Aim To optimize the alcohol extraction process of gongxueyin granules.Methods The alcohol extraction process of gongxueyin granules was optimized by the orthogonal design,with peoniflorin,ginsenoside Rg 1 and the extractum as the indicators.Results The optimal process was adding 18 times 70% alcohol into herbal pieces,then reflux extracting 3 times and 2 hours each time.Conclusion The optimal extraction process is stable and reasonable. |
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| Keywords: | gongxueyin granules peoniflorin ginsenoside Rg 1 alcohol extraction process |
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