| 服用“复方炔雌醚”妇女的外周血淋巴细胞姐妹染色单体互换的研究 |
| |
| 引用本文： | 张忠恕,谈涌布,吕群,陆湘云,于传鑫,颜本元. 服用“复方炔雌醚”妇女的外周血淋巴细胞姐妹染色单体互换的研究[J]. 生殖与避孕, 1982, 0(4) |
| |
| 作者姓名： | 张忠恕 谈涌布 吕群 陆湘云 于传鑫 颜本元 |
| |
| 作者单位： | 上海复旦大学遗传学研究所，上海复旦大学遗传学研究所，上海复旦大学遗传学研究所，上海第一医学院妇产科医院，上海第一医学院妇产科医院，上海第一医学院妇产科医院 上海市计划生育科学研究所，上海市计划生育科学研究所 |
| |
| 摘 要： | 本文研究长效口服避孕药复方炔雌醚(内含炔雌醚3.3毫克和氯地孕酮15毫克)对妇女外周血淋巴细胞姐妹染色单体互换(SCE)率的影响。结果,服药妇女每个细胞SCE率平均值为3.55±0.41(S.E),和正常妇女的3.22±0.41(S.E)比较,两者差异没有统计学意义(P>0.05)。表明复方炔雌醚不具有明显的DNA 初级损伤效应。
|
STUDIES ON SISTER CHROMATID EXCHANGE IN PERIPHERAL BLOOD LYMPHOCYTES FROM WOMEN TAKING LONG-ACTING ORAL CONTRACEPTIVES(COMPOUND QUINESTROL) |
| |
| Abstract: | The effect of the long-term use of a long-acting contraceptive(containing 3.3 mgquinestrol and 15 mg chlormadinone in a tablet),one tablet a month,on the frequencyof sister chromatid exchanges(SCEs)was investigated.The mean frequency of SCE percell was 3.55±0.41(S.E)in women taking oral contraceptives,compared with 3.22±0.40(S.E)in normal healthy women who had never been taking this kind of drug.Thedifference was not statistically significant(p>0.05).This result suggests that the SCE frequency of the peripheral blood lymphocytes is notincreased in women taking the long-acting oral contraceptive,and this drug probably hasnot any apparent DNA primary damage effect. |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
|
