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昂丹司琼对肺癌化疗所致恶心呕吐的预防
引用本文:邱栋发,黄窕姮,张招莲. 昂丹司琼对肺癌化疗所致恶心呕吐的预防[J]. 医药导报, 2001, 20(3): 180-181
作者姓名:邱栋发  黄窕姮  张招莲
作者单位:福建省三明市第一医院呼吸内科,
摘    要:目的:评价单剂昂丹司琼对肺癌化疗所致恶心、呕吐的预防作用。方法:选择35例肺癌化疗患者,采用自身交替对照的方法,观察单次静脉注射昂丹司琼8mg对化疗所致恶心、呕吐的预防作用。结果:单剂昂丹司琼对肺癌化疗所致恶心、呕吐的控制率分别为91.4%、94.3%;甲氧氯普胺的控制率分别为65.7%,74.3%,两者比较差异显著。结论:单剂昂丹司琼对肺癌化疗所致恶心、呕吐有明显的预防作用。

关 键 词:昂丹司琼 甲氯氯普胺 肺癌 呕吐 药物疗法 化疗 预防
文章编号:1004-0781(2001)03-0180-02
修稿时间:2000-02-23

The Effect of Ondansetronin Prevention of Chemotherapy-induced Nausea and Vomitus in Lung Cancer Patients
QIU Dong-fa,HUANG Tiao-heng,ZHANG Zhao-lian. The Effect of Ondansetronin Prevention of Chemotherapy-induced Nausea and Vomitus in Lung Cancer Patients[J]. Herald of Medicine, 2001, 20(3): 180-181
Authors:QIU Dong-fa  HUANG Tiao-heng  ZHANG Zhao-lian
Abstract:Objective:To evaluate the effect of single-dose ondansetron in prevention of chemotherapy-induced nausea and vomitus in lung cancer patients. Methods:35 lung cancer patients receiving chemotherapy were observed with self-comparisonal design. A single dose of 8mg ondansetron and of 20mg metoclopramide were administered by intravenous injection and intramuscular in jection to the patients at different time and the outcome was observed. Results:The control rates of nausea and vomitus by ondansetron were 91.4% and 94.3%, and 65.7% and 74.3% by metoclopramide respectively(P<0.05). Conclusion:A single-dose of ondansetron can effectively prevent nausea and vomitus in lung cancer patients caused by chemotherapy.
Keywords:Ondansetron  Metoclopramide  Lung cancer  Chemotherapy  Vomitus
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