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急性脑梗死与胰岛素抵抗及胰岛素抗体水平相关性分析
引用本文:蔚志刚,秦晓凌,陈国芳,张侠,黄文娟.急性脑梗死与胰岛素抵抗及胰岛素抗体水平相关性分析[J].神经病学与神经康复学杂志,2010,7(2).
作者姓名:蔚志刚  秦晓凌  陈国芳  张侠  黄文娟
作者单位:江苏省徐州市中心医院神经内科,徐州,221009
摘    要:目的 探讨急性脑梗死(ACI)与胰岛素抵抗(IR)及胰岛素抗体(IAb)水平之间的相关性.方法 采用放射免疫法测定34例ACI组,28例ACI恢复期组及30名健康对照者的空腹血胰岛素(INS)、IAb水平,同时检测空腹血糖(FBG)、血脂,计算胰岛素敏感指数(ISI).结果 ACI组INS、IAb显著高于恢复期组及对照组;ISI较对照组显著降低.结论 ACI患者存在明显IR,血IAb水平亦显著增高,IR及IAb可能参与了ACI的发病过程.

关 键 词:胰岛素抵抗  胰岛素抗体  急性脑梗死

Analysis of the relationship between insulin resistance and insulin antibody in the patients with acute cerebral infarction
Yu Zhigang,Qin Xiaoling,Chen Guofang,Zhang Xia,Huang Wenjuan.Analysis of the relationship between insulin resistance and insulin antibody in the patients with acute cerebral infarction[J].Journal of Neurology and Neurorehabilitation,2010,7(2).
Authors:Yu Zhigang  Qin Xiaoling  Chen Guofang  Zhang Xia  Huang Wenjuan
Institution:Yu Zhigang,Qin Xiaoling,Chen Guofang,Zhang Xia,Huang Wenjuan(Department of Neurology,Xuzhou Municipal Center Hospital,Xuzhou 221009,Jiangsu Province,China)
Abstract:Objective To investigate the relationship between acute cerebral infarction(ACI) and insulin resistance(IR) and insulin antibody(IAb) levels.Methods Fasting serum insulin(INS) and IAb levels were determined by radioimmunoassay in 34 patients with ACI,28 patients in the convalescent stage and 30 healthy control subjects.Fasting blood glucose(FBG),blood lipid were measured and insulin sensitivity index(ISI) were calculated as well.Results Compared with the convalescent stage patients and the control subjects,...
Keywords:insulin resistance  insulin antibody  acute cerebral infarction  
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