针吸活检对肺癌诊断准确性的探讨

目的 探讨针吸活检诊断肺癌的准确性和应用价值。方法 CT引导下对肺部病变进行针吸活检术，针吸获得物制成涂片，对有组织块的标本进行常规石蜡包埋切片，所有标本均HE染色。收集有术后组织学对比的81例病例结果进行回顾性分析。结果 穿刺涂片定性诊断准确率85．2％（69／81），穿刺组织切片为86．2％（56／65），两者结合为91．4％（74／81）。穿刺组织切片对肺癌分型诊断准确率为94．6％（53／56），比穿刺涂片的69．6％（48／69）高（P〈0．01）。结论 细针穿刺涂片与穿刺组织切片的诊断准确性均较高，后者对肺癌的分型有更高的应用价值。

Study on diagnostic accuracy of aspiration biopsy of lung cancer

Objective To study on the diagnostic accuracy and value of aspiration biopsy of lung cancer. Methods CT-FNA biopsy was performed in lung-lesion cases. All the samples obtained were prepared into smears and the tissue blocks found were made into mini-tissue sections with paraffin embedded and HE stained. Then 81 cases with postoperative histologic diagnosis were collected and analysed retrospectively. Results The diagnosis sensitivity of CT-FNA smears and CT-FNA tissue sections were 85.2% (69/81) and 86. 2% (56/65) respectively. The figure of overall sensitivity was 91. 4% (74/81) when the two procedures were combined. In aspect of histological typing, the diagnostic accuracy of FNA tissue section (94. 6%) was significantly higher than of FNA smear (69. 6%) (P<0. 01). Conclusion The diagnostic accuracy of FNA smears and FNA tissue sections are high, whereas the latter is more valuable in histologic typing.