Cerebral Damage Following a Single High Exposure to Carbon Disulphide |
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| Authors: | Kruse, Anders Borch-Johnsen, Knut Pedersen, Lisbet Milling |
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| Affiliation: | Clinic of Occupational Medicine, Rigshospitalet, University Teaching Hospital Copenhagen, Denmark |
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| Abstract: | A formerly healthy 48-year-old man was accidentally exposedfor approximately 20 minutes to a high concentration of carbondisulphide (minimum concentration, 400 parts/106; maximum, 470000 parts/106), and was unconscious for approximately 10 minutes.Serious persistent cerebral deterioration developed. Computerizedtomography scanning showed cerebral atrophy, neuro-psychologicalexamination established dementia, and measurement of cerebralflow showed reduced cortical flow in the right hemisphere. Possible mechanisms for the cerebral damage are discussed, andpersons who are at risk from such accidental poisoning are listed. Accepted 1 August 1981 |
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