99mTc-GSA SPECT/CT fusion imaging for hepatectomy candidates with extremely deteriorated ICG value |
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| Authors: | Tatsuaki Sumiyoshi Takehiro Okabayashi Yuji Negoro Yasuhiro Hata Yoshihiro Noda Kenta Sui Jun Iwata Manabu Matsumoto |
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| Affiliation: | 1.Department of Gastroenterological Surgery,Kochi Health Sciences Center,Kochi,Japan;2.Department of Medical Oncology,Kochi Health Sciences Center,Kochi,Japan;3.Department of Radiology,Kochi Health Sciences Center,Kochi,Japan;4.Department of Diagnostic Pathology,Kochi Health Sciences Center,Kochi,Japan |
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| Abstract: | PurposeThe value of indocyanine green (ICG) test is negatively affected in patients with intrahepatic shunt, ICG excretory defect, or jaundice. This study evaluated 99mTc-GSA SPECT/CT fusion imaging for assessing liver function in patients with severely deteriorated ICG values.Materials and methodsThirteen hepatectomy candidates with ICG retention rates over 40% were retrospectively analyzed. The ICG clearance rate (KICG) and estimated KICG obtained by 99mTc-GSA scintigraphy (KGSA) were used to evaluate preoperative whole liver function. Remnant liver function was assessed using the remnant (rem) KICG (=?KICG?×?volumetric rate) and remKGSA (=?KGSA?×?functional rate) indices; hepatectomy was considered unsafe for values ResultsKGSA values were significantly greater than KICG values (median: 0.12 vs. 0.059; p?p? Conclusions99mTc-GSA SPECT/CT fusion imaging enables more accurate liver function assessment than the ICG test in patients with severely deteriorated ICG values. |
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