Benzhydroxamsäuren aus Nifedipin und der korrespondierenden 1,2-Dihydropyridin-Verbindung

Benzohydroxamic Acids from Nifedipine and the Corresponding 1,2-Di-hydropyridine Compound The nitro compounds 1 and 2 have been reduced to the phenylhydroxylamines 3 and 4 and transformed into the benzhydroxamic acids 5 and 6 . From the reduction of the 1,2-dihydropyridine 2 the 2,6-methano-1,5-benzodiazocine 10 could be isolated as a by-product. All dihydropyridines are characterized by their half-wave potentials, their retention times obtained by hplc and spectrometric methods.