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Squamous Cell Carcinoma of the Upper Aerodigestive Tract Associated With WellDifferentiated Carcinoma of the Thyroid Gland
Authors:Luis Pacheco-Ojeda  Christian Micheau  Bernard Luboinski  Jean Richard  Jean-Paul Travagli  Guy Schwaab  Patrick Marandas
Abstract:The association of squamous cell carcinoma of the upper aerodigestive tract with well-differentiated thyroid carcinomas has rarely been reported in the literature. We report 10 cases illustrating this occurrence. In eight cases, the thyroid carcinoma was discovered accidentally on histological examination of a single neck node, a neck node dissection specimen, an unexpectedly found thyroid nodule, or a systematically resected thyroid lobe, all during surgical treatment of an upper aerodigestive tract carcinoma. In the other two cases, metastatic thyroid neck nodes appeared during the follow-up of a patient with an upper aerodigestive tract carcinoma. No case of upper aerodigestive tract carcinomas was found during the follow-up of thyroid cancer patients. In most cases, adequate thyroid cancer surgery was performed simultaneously or later. Prognosis was essentially determined by the upper aerodigestive tract cancer.
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