2005年汕头市流感病原学和血清学流行病学调查

目的分析和掌握汕头市流感变化特点和流行趋势。方法2005年1～12月采集市区流感样病人的咽拭子标本405人份进行流感病毒分离,共分离出流感病毒33株,分离率为8.15%,其中23株为A(H3N2)亚型,10株为A(H1N1)亚型。采集一般人群血清100人份,采用微量半加敏血凝抑制试验(HI)进行A(H1N1)型、A(H3N2)型、B(Victoria系)型、B(Yamagata系)型抗体水平测定。结果阳性率分别是:35.00%、73.00%、16.00%、9.00%。采集职业人群血清90人份进行H5N1抗体水平测定,阳性率为0。结论汕头市人群未受禽流感病毒感染,2005年流行优势株为A(H3N2)亚型,人群对A(H1N1)型和B型流感病毒的免疫力较低,需引起注意。

Epidemiological study of aetiology and serology on influenza in Shantou City in 2005

Objective The study was designed to analyze and understand the changing characteristic and epidemic trend of influenza in Shantou City.Methods From January to December in 2005,total 405 person-specimens of throat swab from influenza patients in the downtown area were sampled for isolation of influenza virus,in which 33 strains of influenza virus,including 23 strains of A(H3N2) and 10 strains of A(H2N2),were obtained,and the isolation rate was 8.15%,and 100 person-specimens of serum from general people were taken for determination of antibodies of A(H1N1),A(H3N2),B(Victoria family) and B(Yamagata family) through micro hemagglutination inhibition(HI) test with virus added to diluted serum for combination of 66 min.Results The positive rates were respectively 35.00%,73.00%,16.00% and 9.00%.The positive rate for H5N1 antibody level determination of 90 person-specimens of serum from professional groups of people was 0.Conclusion The people in Shantou City have not been infected by avian influenza virus,and the strain of A(H3N2) was the predominant in 2005.The immunity of people for influenza A(H1N1) and B viruses is low,which should be taken seriously.