球后注射联合云克治疗Graves眼病的疗效观察及护理

目的探讨33例球后注射联合静脉注射云克治疗Graves眼病的疗效观察及护理。方法用甲泼尼龙琥珀酸钠20 mg+维生素B120.5ug球后注射,联合静脉注射云克11 mg(鍀99TC]亚甲基二膦酸盐注射液),每日1次,5次为1个疗程,注射1个疗程休息2周,连续注射5个疗程,3个月后随访观察记录自觉症状、眼征情况。结果 33例(59眼)患者接受治疗,显效率30.51%(18/59),有效率62.71%(37/59),无效率6.78%(4/59),总有效率93.22%;大部分患者畏光、流泪、眼胀眼痛等症状及充血水肿、眼睑浮肿等体征得到明显改善或消失。结论球后注射联合静脉注射云克治疗甲状腺相关眼病效果显著,不良反应小,安全性高。

THERAPEUTIC EVALUATION AND NURSING CARE OF RETROBULBAR INJECTION COMBINE WITH INTRAVENOUS INJECTION OF MDP FOR OPHTHALMIC GRAVES′ DISEASE

Objective To investigate therapeutic evaluation and nursing care to 33 cases （59 eyes） of Oph- thalmic Graves＇ disease patients which received retrobulbar injection combine with intravenous injection of MDP. Methods Retrobulbar injection with methylpre dnisolone sodium succinate （ methylpre - dnisolone sodium succinate 20 mg＋ Vitamin B12 O. 5 ixg） combine with intra - venous injection of MDP（ Technetium 99TC ] methylene diphos- phonate injection, llmg）, one time per day, 5 times for a course of treatment. Rest for two weeks after each course, continuous injection for 5 courses. To follow - up the obsetv - ation to symptoms and eye situation of patients after 3 months. Results 33 patients（59 eyes） received the treatment, significant effect rate 30. 51% （18/59）,effect rate 62. 71% （37/59）, in effect rate 6.78（4/59） ,total effect rate 93.22% ; The symptoms of phtophobia, watery eyes, eye pain and the sign of swelling, edema with eyelid in most patients had significant improve or disappear. Conclu- sion Effect of treatment with retrobulbar injection combine with intravenous injection of MDP to Ophthalmic Graves＇ disease was significant, adverse reations and safty.