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小功率无线电能传输系统对小鼠记忆行为和部分生理特性影响的研究
引用本文:赵军,杨婷,王磊,武志军.小功率无线电能传输系统对小鼠记忆行为和部分生理特性影响的研究[J].生物医学工程学杂志,2020(2):280-287,295.
作者姓名:赵军  杨婷  王磊  武志军
作者单位:河北工业大学;河北工业大学;中国医学科学院
基金项目:国家自然科学基金项目(51407058);国家电网公司科技项目(5442DG170008)。
摘    要:无线电能传输(WPT)是一种新型的电能传输方式,被广泛应用于电动汽车等各个领域。为保证无线电能传输系统的安全使用,必须分析其电磁环境的安全性。本实验搭建了小功率无线电能传输实验平台,接收功率25 W,谐振频率47 kHz,开展了动物暴露实验。小鼠在无线电能传输电磁环境下每天暴露5 h,6天为一个周期,每个周期后测试小鼠工作记忆能力,实验连续12周。实验结束后检测各只小鼠血清中的免疫参数、性激素含量和部分器官的生理结构。实验结果发现,小鼠的的记忆行为没有随着暴露时间的增加出现明显的变化,性激素含量无明显变化(P> 0.05),免疫因子如肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)、白细胞介素-1β(IL-1β)含量均明显升高(P <0.05),部分器官结构有一定的改变。实验结果表明,搭建的无线电能传输系统环境对小鼠记忆行为无影响,而对小鼠生理特性有一定的影响。

关 键 词:无线电能传输  电磁暴露  记忆行为  免疫特性  器官生理结构

Effects of low-power wireless power transfer system on memory behavior and part of physiological properties of mice
ZHAOJun,YANG Ting,WANG Lei,WU Zhijun.Effects of low-power wireless power transfer system on memory behavior and part of physiological properties of mice[J].Journal of Biomedical Engineering,2020(2):280-287,295.
Authors:ZHAOJun  YANG Ting  WANG Lei  WU Zhijun
Institution:(State Key Laboratory of Reliability and Intelligence of Electrical Equipment,Hebei University of Technology,Tianjin 300130,P.R.China;Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability of Hebei Province,Hebei University of Technology,Tianjin 300130,P.R.China;Chinese Academy of Medical&Peking Union Medical College Institute of Biomedical Engineer,Tianjin 300192,P.R.China)
Abstract:Wireless power transfer(WPT) is a new power transmission way, which can be widely used in electric vehicles and other fields. Its electromagnetic environment must be analyzed to ensure safe application. A low-power wireless power transfer system experimental platform was built, with 25 W receiving power and 47 kHz resonant frequency, which was used to carry out animal experiments. Treatment mice were exposed to environment of wireless power transfer system for 5 h a day and 6 days as one cycle. At the end of every cycle, learning memory behavior of mice were detected in T-shaped maze. The exposure experiment lasted for 12 weeks. Finally, immune parameters, sex hormones and part of organ physiological structure were detected. The results are as follows: as exposure time increased, memory behavior of mice did not change obviously with no statistical difference in sex hormone either(P > 0.05), the concentration of immune factors including tumor necrosis factor-α(TNF-α), interleukin 6(IL-6) and interleukin-1 beta(IL-1β) significantly increased(P < 0.05), and the structure of some organs showed some changes. The experimental results show that the environment of the wireless power transfer system has no effect on the memory behavior of mice,and has some effect on physiological properties of mice.
Keywords:wireless power transfer  radiation exposure  memory behavior  immunity  organ physiology
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