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心力衰竭患者血浆B型尿钠肽水平与D-二聚体的相关性分析
引用本文:周武,王明山,黄小芳,吕美艳,杨丽红. 心力衰竭患者血浆B型尿钠肽水平与D-二聚体的相关性分析[J]. 重庆医学, 2008, 37(8): 858-859
作者姓名:周武  王明山  黄小芳  吕美艳  杨丽红
作者单位:浙江省温州医学院附属第一医院检验科,325000;浙江省温州医学院附属第一医院检验科,325000;浙江省温州医学院附属第一医院检验科,325000;浙江省温州医学院附属第一医院检验科,325000;浙江省温州医学院附属第一医院检验科,325000
摘    要:目的探讨冠心病患者心力衰竭时血浆B型尿钠肽(BNP)及D-二聚体(D-D)水平的变化,以及两者的关系。方法检测了79例冠心病心力衰竭患者和20例健康体检者的血浆BNP及D-二聚体水平,并加以比较和作相关性分析。结果冠心病患者心力衰竭时血浆BNP及D-D水平均明显高于对照组(P<0.01),且BNP与D-二聚体水平呈对数正相关(r=0.4398,t=4.2970,P<0.05)。结论冠心病患者心力衰竭时BNP分泌增加,继发性纤溶功能亢进;BNP与D-二聚体两者间存在一定相关性。

关 键 词:心力衰竭  B型尿钠肽  D-二聚体
文章编号:1671-8348(2008)08-0858-02
修稿时间:2007-10-14

Correlation between B-type natriuretic peptide and D-dimer in patients with heart failure
ZHOU Wu,WANG Ming-shan,HUANG Xiao-fang,et al.. Correlation between B-type natriuretic peptide and D-dimer in patients with heart failure[J]. Chongqing Medical Journal, 2008, 37(8): 858-859
Authors:ZHOU Wu  WANG Ming-shan  HUANG Xiao-fang  et al.
Abstract:Objective To elucidate the correlation between B-type natriuretic peptide(BNP) and D-dimer in patients with heart failure.Methods BNP, D-dimer were assessed in 79 paients with heart failure and 20 normal controls.Results (1) The serum BNP and D-dimer were higher in patients with heart failure than that in normal controls(P<0.001).(2) There were positive correlation(P<0.001)between serum BNP and D-dimer in patients with heart failure.Conclusion (1)The patients with heart failure are abnormal coagulative and fibrinolytic system .(2) BNP is correlated with serum D-dimer and increased in patients with heart failure.
Keywords:heart failure  B-type natriuretic peptide  D-dimer
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