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A primary cardiac sarcoma presenting with superior vena cava obstruction
Authors:Thakker Manish  Keteepe-Arachi Tracey  Abbas Ausami  Barker Graham  Ruparelia Neil  Kingston Gearoid T  Parke Timothy J
Institution:
  • ST4 in Emergency Medicine, Department of Emergency Medicine, Stoke Mandeville Hospital, Aylesbury, UK;
  • Department of Cardiology, Royal Berkshire Hospital NHS Trust, Reading, UK;
  • Department of Radiology, Southampton University Hospitals NHS Trust, Southampton, UK;
  • Department of Anaesthesia and Intensive Care, Oxford Radcliffe Hospitals NHS Trust, Oxford, UK;
  • Department of Cardiology, Royal Berkshire Hospital NHS Trust, Reading, UK;
  • Department of Cellular Pathology, Royal Berkshire Hospital NHS Trust, Reading, UK;
  • Department of Anaesthesia and Intensive Care, Royal Berkshire Hospital NHS Trust, Reading, UK
  • Abstract:Superior vena cava (SVC) obstruction leads to a constellation of symptoms and signs that encompass the SVC syndrome. Today, malignancy accounts for 65% of all cases. The most common neoplastic causes are non–small cell lung cancer (50%), small cell lung cancer (25%), lymphoma, and metastasis. Primary cardiac tumors are an extremely rare cause of SVC obstruction. We describe the case of a 48-year-old man who presented with dyspnea, confusion, and facial swelling with cyanosis. The patient developed life-threatening airway obstruction after administration of anxiolytic. The diagnosis of SVC obstruction secondary to a primary cardiac sarcoma was established based on clinical, radiologic, and post-mortem findings. This is one of very few reported cases of a primary cardiac sarcoma causing SVC obstruction.
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