阿托伐他汀治疗非缺血性心脏病慢性心衰的临床效果

目的 探讨阿托伐他汀治疗非缺血性心脏病慢性心衰的临床效果,为该病的治疗提供临床依据.方法 选择2008年1月至20110年6月在我院内科进行治疗的非缺血性心脏病慢性心衰患者共93例,按照就诊顺序随机分为治疗组和对照组,观察并比较两组患者的治疗效果、治疗前后的心功能和心脏指标的变化.结果 治疗组治疗总有效率为89.13%(41/46),而对照组治疗总有效率为63.83%(30/47),治疗组高于对照组(P＜0.05).治疗前,两组患者左心室射血分数和左心室舒张末内径差异无统计学意义(P＞0.05);治疗后,两组患者左心室射血分数均有明显提高,左心室舒张末内径均有明显改善,两组治疗前后差异均具有统计学意义(P＜0.05),且治疗后治疗组在左心室射血分数的提高和左心室舒张末内径的改善上均优于对照组(P＜0.05).结论 阿托伐他汀治疗非缺血性心脏病慢性心衰具有良好的效果,可以在临床实践中推广应用.

The Clinical Effect of Atorvastatin Treatment on Chronic Heart Failure of Ischemic Heart Disease Patients

Aim To study the clinical effects of atorvastatin treatment on chronic heart failure of non-ischemic heart disease,as the basis for clinical treatment of the disease. Methods 93 cases with chronic heart failure of non-ischemic heart disease from January 2008 to June 2010 Division I hospital for treatment were selected,and in accordance with the treatment randomly divided into treatment group and control group.Heart function and cardiac indices were observed and compared before and after treatment in the two groups. Results The total effective rate was 89.13%(41/46) in the treatment group,while the control group was only 63.83%(30/47).The total effective rate in the treatment group was higher than that in the control group(P<0.05).Before treatment,LVEF and LVDD had no significant difference in the two groups(P>0.05).After treatment,LVEF and LVDD were significantly improved in the two groups(P<0.05),and the improvement of LVEF and LVDD in the treatment group were better than those in the control group(P<0.05). Conclusions Atorvastatin treatment of non-ischemic heart disease with chronic heart failure has a good therapeutic effect,which can be widely applied in clinical practice.