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新型抗精神病药所致体重增加的对照研究
引用本文:刘晓鹏,林莉,范玉霞,董学丽.新型抗精神病药所致体重增加的对照研究[J].中国民康医学,2003,15(4):230-231.
作者姓名:刘晓鹏  林莉  范玉霞  董学丽
作者单位:1. 山东省临沂市荣军医院,276005
2. 山东省临沂市中医医院,山东,临沂,276002
摘    要:目的:比较新型抗精神病药物氯氮平、利培酮、奎的平对精神病病人体重的影响。方法:将40例精神分裂症病人随机分为氯氮平组和利培酮或奎的平组各20例,进行为期6周的临床观察。结果:氯氮平组体重明显增加,平均增重1.63kg。治疗前后经统计学处理,差异有显性(P<0.05)。利培酮或奎的平组体重虽有增加趋势,但治疗前后差异无显性(P>0.05)。结论:氯氮平易导致病人的体重增加,利培酮奎的平对体重影响较轻,临床医师应予以关注。

关 键 词:新型抗精神病药  氯氮平  利培酮  奎的平  不良反应  体重增加  比较
文章编号:1672-0369(2003)04-0230-02
修稿时间:2002年5月21日

A Comparative study of new-Anti-psychopathic drugs lead to gain weight
Liu Xiao-peng ,Lin Li ,et al.A Comparative study of new-Anti-psychopathic drugs lead to gain weight[J].medical journal of chinese peoples health,2003,15(4):230-231.
Authors:Liu Xiao-peng  Lin Li  
Institution:Liu Xiao-peng 1,Lin Li 2,et al
Abstract:Objective:To compare cl ozapine and Risperidone or guetiap ine influence on body weight of sc hizophrenic patients Methods:40 ca ses of schizophrenic patients were assigned randomly average to cloza pine ond Risperidone or quetiapine treatment for 6 weeks Results:the clozapine's group gained body weig ht obviously after treatment avera ge gain weight was 1 63kg there was significan difference in the cloza pine's group However Risperidone o r quetiapine's group tends to incr ease the body weight but there was no significant difference,after tre atment Conclusions:clozapine leads to gain weight easily Risperidone or quetiapine has a less influence on body weight than clozapine the clinical doctors should pay attent ion to gain weight side effect on schizophrenic patients after treat ment
Keywords:clozapine  Risperiedone  quetiapine  body  weight
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