胸膜肺切除治疗肺癌胸膜转移伴癌性胸水病人的临床分析

目的：探讨以外科为主的综合治疗对肺癌胸膜转移伴癌性胸水病人治疗的新途径。方法：应用胸膜全肺切除为主的综合治疗对55例符合手术标准的肺癌胸膜转移伴癌性胸水的病人进行治疗，并随访。结果：55例病人中2例因手术后并发症死亡，其余53例术后病情缓解，症状明显改善。经1～25年随访，48例病人生存期为5～4。个月，中位生存期14个月，5例病人仍健在。结论：严格掌握手术适应证，尽可能切除彻底，可提高患者的生存质量并延长生存期。

Clinical analysis of pleuropneumonectomy for lung cancer with diffuse pleural metastasis accompanied by malignant pleural effusion

Objective To investigate a novel therapeutic strategy in the treatment of lung cancer with diffuse pleural metastasis accompanied by malignant pleural effusion. Methods From December 1978 to February 2003, 55 patients of carcinoma of lung with pleural metastasis underwent the comprehensive therapy characterized by pleuropneumonectomy. A follow-up of all the patients after hospital discharge was conducted. Results Death due to complications was found in 2 out of the 55 patients, but remission and significant improvement of symptoms were found in the rest. A follow-up period ranging from 1 to 25 years revealed that 48 patients survived for 5-40 months (median survival time: 14 months), and 5 patients were still living and well. Conclusion Strict control of the surgical indications and radical removal of the malignant tumor can improve the quality of life and prolong the survival time of patients, even there is already metastasis to the pleura.