| 三乙醇胺染毒大鼠对碱性磷酸酶的抑制类型的作用 |
| |
| 引用本文： | 孙凤祥,严庆涛,赵泮梅,任维栋. 三乙醇胺染毒大鼠对碱性磷酸酶的抑制类型的作用[J]. 潍坊医学院学报, 2002, 24(3): 195-196 |
| |
| 作者姓名： | 孙凤祥 严庆涛 赵泮梅 任维栋 |
| |
| 作者单位： | 1. 潍坊医学院生化教研室,山东,潍坊,261042
2. 潍坊医学院附属潍坊市人民医院 |
| |
| 摘 要： | 目的 实验测定三乙醇胺对大鼠碱性磷酸酶 (ALP)活性的影响。方法 按照经典酶学方法 ,观察不同浓度三乙醇胺对大鼠血清ALP的抑制作用 ,探讨三乙醇胺对溶液ALP的抑制类型 ,用Dixon和Cronish Bowden作图法分别求出Ki与Ki’。结果 三乙醇胺对溶液ALP的抑制作用属混合型抑制作用 ,其Ki=0 .0 2 4mmol L ;Ki’ =0 .0 0 65mmol L。结论 三乙醇胺对大鼠血清ALP有混合型抑制作用。
|
| 关 键 词： | 三乙醇胺 碱性磷酸酶 抑制作用 |
| 文章编号： | 1004-3101(2002)03-0195-02 |
| 修稿时间： | 2001-11-04 |
The Research of Inhibition Type of Triethanolamine the Serum ALP of The Rats |
| |
| SUN Feng xiang,YAN Qing tao ,ZHAO Pan mei ,REN Wei dong. The Research of Inhibition Type of Triethanolamine the Serum ALP of The Rats[J]. Journal of Weifang Medical College, 2002, 24(3): 195-196 |
| |
| Authors: | SUN Feng xiang YAN Qing tao ZHAO Pan mei REN Wei dong |
| |
| Affiliation: | SUN Feng xiang,YAN Qing tao *,ZHAO Pan mei *,REN Wei dong |
| |
| Abstract: | Objective To study the effect of triethanolamine on the activity of rat alkaline phosphatase(ALP).Method The inhibition types of triethanolamine on nature ALP was determined by ways of classic enzymatic methods; The inhibition constant Ki and Ki' were given in Dixon's and Cronish Brwden's figure espectively.Result The inhibition type of triethylamine on activity of nature ALP was mixed inhibition.Its Ki=0.024mmol/L,Ki'=0.0065 mmol/L.Conclusion Triethanolamine has mixed inhibition to serum ALP of rats. |
| |
| Keywords: | Triethanolamine ALP Inhibition |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
