| 大骨节病患区与非患区胎儿软骨基质酸性粘多糖的组织化学研究 |
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| 引用本文： | 刘井福,翁玉璞,金军,王春艳,吕孝普,魏赤平,李光芝,任宏造.大骨节病患区与非患区胎儿软骨基质酸性粘多糖的组织化学研究[J].中国地方病学杂志,1987(5). |
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| 作者姓名： | 刘井福 翁玉璞 金军 王春艳 吕孝普 魏赤平 李光芝 任宏造 |
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| 作者单位： | 辽宁省基础医学研究所
(刘井福，翁玉璞，吕孝普，魏赤平，李光芝)，陕西省咸阳地区地方病防治研究所
(金军)，内蒙呼盟阿荣旗妇幼保健站
(王春艳)，辽宁省基础医学研究所(任宏造) |
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| 摘 要： | 提要 本文对大骨节病患区与非患区胎儿软骨基质酸性粘多糖进行了组织化学研究。发现患区胎儿软骨基质中透明质酸(HA)高于非患区;Chs—A/C 低于非患区,这些可能是基质过早钙化的原因。
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| 关 键 词： | 大骨节病 组织化学 |
STUDIES OF HISTOCHEMISTRY OF ACID MUCOPOLYSACCHARIDES ON CARTILAGE MATRIX OF EMBRYO BETWEEN ENDEMIC AND NON-ENDEMIC AREAS OF KASCHIN-BECK'S DISEASE |
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| Liu Jingfu,et al.STUDIES OF HISTOCHEMISTRY OF ACID MUCOPOLYSACCHARIDES ON CARTILAGE MATRIX OF EMBRYO BETWEEN ENDEMIC AND NON-ENDEMIC AREAS OF KASCHIN-BECK''''S DISEASE[J].Chinese Jouranl of Endemiology,1987(5). |
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| Authors: | Liu Jingfu |
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| Abstract: | The studies attempt to describe whether or not embryo may be sufferedfrom kaschin(?)beck's disease.In this paper it is observed that hyaluronicacid of embryo cartilage matrix of endemic areas are higher;chondroitin sul(?)fate A and C(chs-A/C)are lower than that of non-endemic areas.In all ofembryo of endemic areas,nagative reaction of chs-A/C was 20-40 percent,and Showed distinct endemicity.The changes above mentioned perhaps revealedthat pathogenic factors disturbed normal metabolism of chs-A/C,and earlypromoted the cartilage matrix to be calcified and aged.we provided the for-mulation for further investigation,as the embryo of the endemic areas mighthave the tendency to be suffered from this disease. |
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| Keywords: | Kaschen-beck's disease Histochemistry |
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