血小板在缺血性脑卒中患者中的研究进展

缺血性脑卒中指大脑供血动脉闭塞或狭窄使脑供血不足而导致的脑组织不同程度受损,主要由动脉粥样硬化及继发血栓形成引起,而血小板在血栓形成过程中发挥着重要作用。缺血性脑卒中的治疗主要以血小板为靶点,但因个体用药依从性差异和缺血性脑卒中高复发等特点,部分缺血性脑卒中患者即使进行了规范的抗血小板治疗但仍存在再发脑卒中风险。本文主要对缺血性脑卒中患者抗血小板治疗、血小板参数及其检测方法进行了综述,以期为再发脑卒中的预防及监测提供参考。

Research Progress on Platelet in Patients with Ischemic Stroke

Ischemic stroke means varying degrees of damage of brain tissue due to cerebral artery occlusion-or stenosis-induced insufficiency of cerebral blood supply,which mainly caused by atherosclerosis and secondary thrombosis,however platelet plays an important role in the process of thrombosis.Platelet-targeted therapy has a leading position in the treatment of ischemic stroke,but there is still high risk of recurrent stroke even after standard anti-platelet therapy in some patients,which may related to difference of individual medication compliance and the characteristic of high risk of recurrence of ischemic stroke.This paper mainly reviewed the anti-platelet therapy,platelet parameters and the detection methods in patients with ischemic stroke,in order to provide a reference for prevention and monitoring of recurrent stroke.