临床诊断为肺肿瘤血栓性微血管病一例并文献复习

肺肿瘤血栓性微血管病(PTTM)是由于肿瘤肺转移而引起的一种少见但致命的并发症,患者生前诊断较困难、预后极差。临床上遇到表现为进行性加重的呼吸困难、干咳、低氧血症、D-二聚体及纤维蛋白降解产物(FDP)升高、肺动脉高压但无肺栓塞证据的患者时需考虑PTTM的可能。本文报道了1例临床诊断为PTTM的患者,并结合国内外文献复习总结了该病的临床特征,以期为提高临床医生对该病的诊断意识提供参考。

Pulmonary Tumor Thrombotic Microangiopathy:a Clinically Diagnosed Case Report and Literature Review

As one of complications caused by tumor lung metastasis,pulmonary tumor thrombotic microangiopathy(PTTM)is rare but fatal,thus it is difficult to be diagnosed before the patient's death,with very poor prognosis.We should think about the possibility of PTTM when found a patient performed as progressive dyspnea,dry cough,hypoxemia,elevation of D-dimer and FDP,pulmonary arterial hypertension without evidence of pulmonary embolism.This paper reported a clinically diagnosed patient with PTTM and summarized the clinical features of PTTM through reviewing literatures at home and abroad,in order to provide a reference for improving the clinical diagnosis consciousness.