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尿微量白蛋白和β2微球蛋白联合检测对糖尿病肾病的诊断价值
引用本文:卢冰贤,周云英.尿微量白蛋白和β2微球蛋白联合检测对糖尿病肾病的诊断价值[J].中国校医,2012,26(3):187-188.
作者姓名:卢冰贤  周云英
作者单位:玉林师范学院医院;
摘    要:目的探讨尿β2微球蛋白(β2-MG)和微量白蛋白(mAlb)对糖尿病肾病早期诊断的价值。方法采用放射免疫法,检测85例糖尿病(DM)患者尿中的β2-MG和mAlb,并与70例健康体检人员作对照。结果 DM患者尿中的β2-MG和mAlb明显高于健康组,两组比较差异有统计学意义(P<0.01)。结论尿β2-MG和mAlb联合检测对糖尿病肾病(DN)的早期诊断有非常重要的临床参考价值,对DM患者早期发现、诊断和治疗肾损害具有重要临床意义。

关 键 词:糖尿病肾病/诊断  白蛋白尿/诊断  β2微球蛋白/尿  

Diagnostic value of microalbuminuria and beta 2 microglobulin united detection for diabetes nephrosis
LU Bing-xian , ZHOU Yun-ying.Diagnostic value of microalbuminuria and beta 2 microglobulin united detection for diabetes nephrosis[J].Chinese Journal of School Doctor,2012,26(3):187-188.
Authors:LU Bing-xian  ZHOU Yun-ying
Institution:First Affiliated Hospital of Medical College,Shantou University,Shantou 515041,Guangdong,China
Abstract:Objective To study the urine beta 2 micro globulin(beta 2-MG) and trace albumin(mAlb) to the early diagnostic value for diabetes nephrosis.Methods A total of 85 patients with diabetes mellitus(DM) were investigated for their urine beta 2-MG and mAlb by radioimmunoassay,and 70 cases of health and medical personnel were as the control. Results The urine beta 2-MG and mAlb of the DM patients was significantly higher than those of healthy group,and there was a significant difference(P<0.01).Conclusions The united detection of urine beta 2-MG and mAlb has a significantly early diagnostic value for DM and diabetic nephropathy(DN).
Keywords:Diabetic Nephropathies/diagnosis  Albuminuria/diagnosis  Beta 2-microglobulin/urine
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