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吡柔比星膀胱内灌注防治浅表性膀胱癌术后复发(附109例报告)
引用本文:吴天麟,张俊杰,王甫剑,韩从辉,梁清,姜波,邱祥政,贺厚光,王阔兴,范涛.吡柔比星膀胱内灌注防治浅表性膀胱癌术后复发(附109例报告)[J].东南大学学报(医学版),2006,25(2):113-115.
作者姓名:吴天麟  张俊杰  王甫剑  韩从辉  梁清  姜波  邱祥政  贺厚光  王阔兴  范涛
作者单位:东南大学医学院附属徐州医院,泌尿外科,江苏,徐州,221009
摘    要:目的:评价吡柔比星膀胱灌注防治膀胱癌术后复发的效果。方法:选择109例膀胱肿瘤患者,给予吡柔比星30mg溶于50ml葡萄糖中行膀胱内灌注,每次保留40,60min,每3,6个月膀胱镜检查1次。术后随访。结果:109例患者随访15,30个月,平均17.5个月,复发11倒,复发率10.1%。结论:吡乘比星膀胱灌注时防治浅表性膀胱癌术后复发效果满意,副作用少。

关 键 词:膀胱肿瘤  吡柔比星  膀胱灌注
文章编号:1671-6264(2006)02-0113-03
修稿时间:2005年6月13日

Prevention and treatment of recurrence of superficial bladder cancer by postoperative intravesical instillation of pirarubicin (report of 109 cases)
WU Tian-lin,ZHANG Jun-jie,WANG Fu-jian,HAN Cong-hui,LIANG Qing,JIANG Bo,QIU Xiang-zheng,HE Hou-guang,WANG Kuo-xing,FAN Tao.Prevention and treatment of recurrence of superficial bladder cancer by postoperative intravesical instillation of pirarubicin (report of 109 cases)[J].Journal of Southeast Univ: Medical Sci Ed,2006,25(2):113-115.
Authors:WU Tian-lin  ZHANG Jun-jie  WANG Fu-jian  HAN Cong-hui  LIANG Qing  JIANG Bo  QIU Xiang-zheng  HE Hou-guang  WANG Kuo-xing  FAN Tao
Abstract:Objective To evaluate effectiveness of instilling pirarubicin(THP) intrvesically after operation of bladder carcinoma to prevent tumor recurrence.Methods 109 patients with superficial bladder carcinoma were instilled intravesically with 30?mg THP added in 50?ml glucose for 40 to 60 minutes in the bladder.Cystoscopy was carried out 3 to 6 months afterwards and all patients had been followed up.Result All patients had been followed up for 15 to 30 months(mean 17.5 months),11 cases had tumor recurrence,the tumor recurrence rate was 10.1%(11/109).Conclusion Intravesical instillation of THP effectively prevents superficial bladder carcinoma from postoperative recurrence with mild side effects.
Keywords:bladder carcinoma  pirarubicin  intravesical instillation
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