慢性丙肝患者不同时期sCRl的检测在临床上的意义

目的：对慢性丙型肝炎患者不同时期血清sCRl浓度进行检测研究，探讨慢性丙型肝炎sCRl浓度变化与该病发生、发展及预后的关系，探索慢性丙型肝炎发生和发展的有效检测指标。结果：①厦性丙型肝炎轻度，中度、重度及肝硬化病人血清sCRl浓度均显著高于正常人群，且慢性丙型肝炎随着病情的发展程度而逐渐升高，重度大于中度，中度大于轻度。②慢性丙型肝炎三组的测定值明显差异性。⑨肝硬化组随着Child．Prlgh分级的升高，其sCRl浓度也随着升高。结论：慢性丙型肝炎病人血清sCRl浓度的变化与肝功能损伤程度密切相关，随着肝硬化程度的加重其浓度也相应的升高，该指标可作为慢性丙型肝炎患者病情严重程度、判断病情发展及预后的重要参考指标。

Clinical significance of the sCR1 detection of chronic hepatitis C patients in different periods

Objective： To detect and research for different periods of chronic hepatitis C patients in serum concentrations ofsCR1. To investigate the relationship between the changes of sCR1 concentration and the occurrence, development and prognosis of chronic hepatitis C. To explore effective detection index of the occurrence and development. Results： （1）Chronic hepatitis C with mild, moderate, severe and the concentration of serum sCR1 in patients with liver cirrhosis were higher than the normal population, and chronic hepatitis C and increased gradually with the development of the severity of the greater than moderate, severe, moderate than the miId.（2）Chronic hepatitis C were determined in three group were significantly different. （3）Cirrhotic patients with Child-Pugh score increased, the sCR1 concentration also increased. Conclusion： Chronic hepatitis C patients with serum sCR1 concentration changes related to the degree of liver dysfimction. With the aggravation of liver cirrhosis concentration also increased, the index can be used as the condition of patients with Chronic hepatitis C, judging the severity of an important reference index for disease develooment and oromaosis.