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复方黄芪肠宁灌肠剂中三七提取工艺的优选
引用本文:张潮林,李勇,曾育君,沈雪梅.复方黄芪肠宁灌肠剂中三七提取工艺的优选[J].广东药学院学报,2008,24(1):25-27.
作者姓名:张潮林  李勇  曾育君  沈雪梅
作者单位:广东药学院中药药剂学教研室,广东,广州,510006;广东药学院药物研究所,广东,广州,510006
基金项目:广东省中医药局(1050045)
摘    要:目的优选复方黄芪肠宁灌肠剂中三七的最佳提取工艺。方法采用正交试验设计,用高效液相色谱法测定提取液中人参皂苷Rg1、人参皂苷Rb1、三七皂苷R1的含量,优选三七药材的提取工艺条件。结果优选的工艺为70%的乙醇6倍量,提取3次,每次1.0 h。结论优选的提取工艺三七总皂苷提取率高,适用于生产。

关 键 词:三七  三七总皂苷  复方黄芪肠宁灌肠剂  正交试验  提取工艺
文章编号:1006-8783(2008)01-0025-03
修稿时间:2007年10月25

Optimum extraction process of saponins from Radix notoginseng for compound Huangqi Changning enema
ZHANG Chao-Lin,LI Yong,ZENG Yu-Jun,SHEN Xue-Mei.Optimum extraction process of saponins from Radix notoginseng for compound Huangqi Changning enema[J].Academic Journal of Guangdong College of Pharmacy,2008,24(1):25-27.
Authors:ZHANG Chao-Lin  LI Yong  ZENG Yu-Jun  SHEN Xue-Mei
Abstract:Objective To optimize the extraction procedure of total saponins from Radix notoginseng for compound Huangqi Changning enemA.Methods Orthogonal test was employed for optimizing the extraction processes by the indexes of the contents of ginsenoside Rg1,ginsenoside Rb1 and notoginsenoside R1.Results Six volumes of 70% alcohol,3 times of extraction processes with 1.0 hour for each time were considered as the optimum extraction technology.ConclusionThis extraction procedure of active components in the drugs is achieved by applying the selected technology.
Keywords:Radix notoginseng  total saponins  compound Huangqi Changning enema  orthogonal design  extraction technology
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